Quantitative Analysis of Isolated and Clustered DNA Damage Induced by Gamma-rays, Carbon Ion Beams, and Iron Ion Beams
نویسندگان
چکیده
منابع مشابه
Quantitative characteristics of clustered DNA damage in irradiated cells by heavy ion beams
Heavy ion beam as typical high linear energy transfer (LET) radiation produces more expanding ionization domain around their tracks than low LET radiation such as X-rays and gamma rays. Thus, heavy ion beam can cause more densely accumulated damage cluster in the target DNA, termed clustered DNA damage. This damage exhibits difficulty for repair and inhibition of DNA replication with its comple...
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The use of radioactive beams opens a new frontier for fusion studies. The coupling to the continuum can be explored with very loosely bound nuclei. Experiments were performed with beams of nuclei at or near the proton and neutron drip-lines to measure fusion and associated reactions in the vicinity of the Coulomb barrier. In addition, the fusion yield is predicted to be enhanced in reactions in...
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Clustered DNA damage (locally multiply damaged site) is thought to be a critical lesion caused by ionizing radiation, and high LET radiation such as heavy ion particles is believed to produce high yields of such damage. Since heavy ion particles are major components of ionizing radiation in a space environment, it is important to clarify the chemical nature and biological consequences of cluste...
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We present the latest advances of the multiscale approach to radiation damage caused by irradiation of a tissue with energetic ions and report the most recent advances in the calculations of complex DNA damage and the effects of thermal spikes on biomolecules. The multiscale approach aims to quantify the most important physical, chemical, and biological phenomena taking place during and followi...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2008
ISSN: 0449-3060,1349-9157
DOI: 10.1269/jrr.07089